IRB Faculty
The Medical &
Scientific Research Directorate
Dr. Mohamood Brobbey Oppong
B.Pharm, MPhil, PhD.
Lecturer- Department of Pharmaceutical Chemistry, University of Ghana School of Pharmacy
mboppong@ug.edu.gh | +233-20-8360510 |
Education
- Bachelor of Pharmacy: Kwame Nkrumah University of Science and Technology, Kumasi, Ghana (2010)
- MPhil, Pharmaceutical Chemistry: Kwame Nkrumah University of Science and Technology, Kumasi, Ghana (2014)
- PhD in Medicinal Chemistry: Tianjin University of Traditional Chinese Medicine, Tianjin, Peoples Republic of China
Board Certifications
- Pharmacy Council, Ghana
Research Interest
My research interests focus on Natural Product Chemistry, Drug Discovery, Analytical Chemistry and Metabolomics.
Current projects
1. Development of analytical method for the qualitative and quantitative detection of the levels of paracetamol and para-aminophenol in soups prepared with paracetamol as tenderizer.
2. Isolation and characterization of secondary metabolites from local medicinal plants.
Current projects
1. Development of analytical method for the qualitative and quantitative detection of the levels of paracetamol and para-aminophenol in soups prepared with paracetamol as tenderizer.
2. Isolation and characterization of secondary metabolites from local medicinal plants.
Selected Publications
PUBLICATIONS
1. Mahmood Brobbey Oppong, Bing-Yang Zhang, Shi-Ming Fang, Feng Qiu (2020). Secondary metabolites from Sterculia lychnophora Hance (Pangdahai). Biochemical and Systemic Ecology, 92, 104125. doi: 10.1016/j.bse.2020.104125
2. Yan-Li Huang, Mahmood Brobbey Oppong, Ying Guo, Li Zhi Wang, Shi-Ming Fang, Yan-Ru Deng, Xu-Mei Gao (2019). The Oleaceae family: A source of secoiridoids with multiple biological activities. Fitoterapia. 136; 104155. doi: 10.1016/j.fitote.2019.04.010
3. Mahmood Brobbey Oppong, Li Yang, Prince Osei Banahene, Fang Shi-Ming, Qiu Feng (2018) Ethnopharmacology, phytochemistry, and pharmacology of Sterculia lychnophora Hance (Pangdahai)Chinese Journal of Natural Medicines. 16(10): 721-731 doi: 10.1016/S1875-5364(18)30112-2s.
4. Xinchi Feng, Yang Li, Mahmood Brobbey Oppong & Feng Qiu (2018) Insights into the intestinal bacterial metabolism of flavonoids and the bioactivities of their microbe-derived ring cleavage metabolites.Drug Metabolism Reviews
5. Cheng-Peng Sun, Mahmood Brobbey Oppong, Feng Zhao, Li-Xia Chen and Feng Qiu (2017) Unprecedented 22,26-seco physalins from Physalis angulata and their anti-inflammatory potential. Organic and biomolecular chemistry, Org. Biomol. Chem., 2017,15, 8700-8704, doi: 10.1039/c7ob02205k
6. Li-Qin Ding, Tian-Yi Qiu, Zhao-Xi Liu, Li-Xia Chen, Mahmood Brobbey Oppong, De-Qin Zhang, Bo-li Zhang, Gang Bai, Feng Qiu (2017) Systematic characterization of the metabolites of paeonol in rats using ultra performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry with an integrative strategy. Journal of Chromatography B 1065–1066 (2017) 70–78
7. Yaqing Guoa, Hongxia Liu, Liqin Ding, Mahmood Oppong, Guixiang Pan, Feng Qiu (2017) LC-MS/MS method for simultaneous determination of flavonoids and physalins in rat plasma: application to pharmacokinetic study after oral administration of Physalis alkekengi var. franchetii (Chinese lantern) extract. doi: 10.1002/bmc.3970
8. John Teye Azietakua, Huifen Maa, Xie-an Yua, Jin Lia, Mahmood Brobbey Oppong, Jun Cao, Mingrui And, Yan-xu Chang (2017) A review of the ethnopharmacology, phytochemistry and pharmacology of Notopterygium incisum, Journal of Ethnopharmacology 202 (2017) 241–255 , doi: 10.1016/j.jep.2017.03.022
9. Nan Zhang, Wei-xing Huang, Gui-yang Xia, Mahmood Brobbey Oppong, Li-qing Ding, Pan Li, Feng Qiu (2017). Methods for determination of absolute configuration of monosaccharides. Chinese Herbal Medicines 10, 14–22, doi: 10.1016/j.chmed.2017.12.009
10. Liwei Chai, Paul Owusu Donkor, Kun Wang, Yingjie Sun, Mahmood Brobbey Oppong, Kai Wang, Liqin Ding & Feng Qiu (2017): Metabolic profiles of corydaline in rats by ultraperformance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry, Xenobiotica, doi: 10.1080/00498254.2017.1416207
11. Jin-Long Yao, Shi-Ming Fang, Rui Liu, Mahmood Brobbey Oppong, Er-Wei Liu, Guan-Wei Fan and Han Zhang (2016) A Review on the Terpenes from Genus Vitex. Molecules 21, 1179
12. Mahmood B. Oppong, Samuel O. Bekoe, Reimel K. Adosraku, John S.K. Ayim. (2015) Simultaneous quantification of five penicillins and detection of penicilloic acid in single and/or multi-component flucloxacillin pharmaceutical formulations.West African Journal of Pharmacy,26 (1) 41-53
13. Newman Osafo ,David Darko Obiri, Kwabena Owusu Danquah, Oduro Kof Yeboah, Aaron Opoku Antwi, Mahmood Brobbey Oppong. Oxidative Stress and Neurodegeneration. In Handbook of Research on Critical Examinations of Neurodegenerative Disorders, Part of the Advances in Medical Diagnosis, Treatment, and Care Book Series. Chapter 2, page 24-47, doi: 10.4018/978-1-5225-5282-6.ch002
1. Mahmood Brobbey Oppong, Bing-Yang Zhang, Shi-Ming Fang, Feng Qiu (2020). Secondary metabolites from Sterculia lychnophora Hance (Pangdahai). Biochemical and Systemic Ecology, 92, 104125. doi: 10.1016/j.bse.2020.104125
2. Yan-Li Huang, Mahmood Brobbey Oppong, Ying Guo, Li Zhi Wang, Shi-Ming Fang, Yan-Ru Deng, Xu-Mei Gao (2019). The Oleaceae family: A source of secoiridoids with multiple biological activities. Fitoterapia. 136; 104155. doi: 10.1016/j.fitote.2019.04.010
3. Mahmood Brobbey Oppong, Li Yang, Prince Osei Banahene, Fang Shi-Ming, Qiu Feng (2018) Ethnopharmacology, phytochemistry, and pharmacology of Sterculia lychnophora Hance (Pangdahai)Chinese Journal of Natural Medicines. 16(10): 721-731 doi: 10.1016/S1875-5364(18)30112-2s.
4. Xinchi Feng, Yang Li, Mahmood Brobbey Oppong & Feng Qiu (2018) Insights into the intestinal bacterial metabolism of flavonoids and the bioactivities of their microbe-derived ring cleavage metabolites.Drug Metabolism Reviews
5. Cheng-Peng Sun, Mahmood Brobbey Oppong, Feng Zhao, Li-Xia Chen and Feng Qiu (2017) Unprecedented 22,26-seco physalins from Physalis angulata and their anti-inflammatory potential. Organic and biomolecular chemistry, Org. Biomol. Chem., 2017,15, 8700-8704, doi: 10.1039/c7ob02205k
6. Li-Qin Ding, Tian-Yi Qiu, Zhao-Xi Liu, Li-Xia Chen, Mahmood Brobbey Oppong, De-Qin Zhang, Bo-li Zhang, Gang Bai, Feng Qiu (2017) Systematic characterization of the metabolites of paeonol in rats using ultra performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry with an integrative strategy. Journal of Chromatography B 1065–1066 (2017) 70–78
7. Yaqing Guoa, Hongxia Liu, Liqin Ding, Mahmood Oppong, Guixiang Pan, Feng Qiu (2017) LC-MS/MS method for simultaneous determination of flavonoids and physalins in rat plasma: application to pharmacokinetic study after oral administration of Physalis alkekengi var. franchetii (Chinese lantern) extract. doi: 10.1002/bmc.3970
8. John Teye Azietakua, Huifen Maa, Xie-an Yua, Jin Lia, Mahmood Brobbey Oppong, Jun Cao, Mingrui And, Yan-xu Chang (2017) A review of the ethnopharmacology, phytochemistry and pharmacology of Notopterygium incisum, Journal of Ethnopharmacology 202 (2017) 241–255 , doi: 10.1016/j.jep.2017.03.022
9. Nan Zhang, Wei-xing Huang, Gui-yang Xia, Mahmood Brobbey Oppong, Li-qing Ding, Pan Li, Feng Qiu (2017). Methods for determination of absolute configuration of monosaccharides. Chinese Herbal Medicines 10, 14–22, doi: 10.1016/j.chmed.2017.12.009
10. Liwei Chai, Paul Owusu Donkor, Kun Wang, Yingjie Sun, Mahmood Brobbey Oppong, Kai Wang, Liqin Ding & Feng Qiu (2017): Metabolic profiles of corydaline in rats by ultraperformance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry, Xenobiotica, doi: 10.1080/00498254.2017.1416207
11. Jin-Long Yao, Shi-Ming Fang, Rui Liu, Mahmood Brobbey Oppong, Er-Wei Liu, Guan-Wei Fan and Han Zhang (2016) A Review on the Terpenes from Genus Vitex. Molecules 21, 1179
12. Mahmood B. Oppong, Samuel O. Bekoe, Reimel K. Adosraku, John S.K. Ayim. (2015) Simultaneous quantification of five penicillins and detection of penicilloic acid in single and/or multi-component flucloxacillin pharmaceutical formulations.West African Journal of Pharmacy,26 (1) 41-53
13. Newman Osafo ,David Darko Obiri, Kwabena Owusu Danquah, Oduro Kof Yeboah, Aaron Opoku Antwi, Mahmood Brobbey Oppong. Oxidative Stress and Neurodegeneration. In Handbook of Research on Critical Examinations of Neurodegenerative Disorders, Part of the Advances in Medical Diagnosis, Treatment, and Care Book Series. Chapter 2, page 24-47, doi: 10.4018/978-1-5225-5282-6.ch002