IRB Faculty
The Medical &
Scientific Research Directorate
Dr. Patrick Amoateng
B.Pharm, PhD.
Senior Lecturer/Head Department, Pharmacology & Toxicology, School of Pharmacy
pamoateng@ug.edu.gh | +233-243-956637 |
Education
- Bachelor of Pharmacy, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana (2005)
- PhD in Pharmacology: Kwame Nkrumah University of Science and Technology, Kumasi, Ghana (2011)
Board Certifications
- Certified Pharmacist, Pharmacy Council, Ghana
Research Interest
My research interests focus on neuropharmacology and drug discovery of neuroactive agents in the areas of epilepsy, pain, psychosis, depression and other related neurological diseases.
Current projects
1.Anticonvulsant drug discovery from medicinal plants in zebrafish models of seizures
2.Antipsychotic drug discovery
3. Discovery of drugs used for neuropathic pain
Selected Publications
1. Mensah JA, Kukuia KKE, Amoateng P, Osei-Safo D, Adongo DW, Ameyaw EO, Ben IO, Amponsah SK, Asiedu-Gyekye IJ. Monoaminergic and L -arginine-no-cGMP pathways mediate the antidepressant–like action of alkaloids from the stem bark of Trichilia monadelpha. Scientific African 2020, e00422
2. Bekoe EO, Agyare C, Boakye YD, Baiden BM, Asase A, Sarkodie J, Nettey H, Adu F, Otu PB, Agyarkwa B, Amoateng P. Ethnomedicinal survey and mutagenic studies of plants used in Accra metropolis, Ghana. Journal of Ethnopharmacology 2019, 112309.
3. Amoateng P, Quansah E, Karikari TK, Asase A, Osei-Safo D, Kukuia KKE, Amponsah IK, Nyarko AK: Medicinal plants used in the treatment of mental and neurological disorders in Ghana. Evidence-Based Complementary & Alternative Medicine 2018.
4. Kukuia KKE, Mensah JA, Amoateng P, Amponsah SK, N'Guessan BB, Asiedu-Gyekye IJ: Antidepressant Potentials of Components from Trichilia monadelpha (Thonn.) J.J. de Wilde in Murine Models. Evidence-Based Complementary & Alternative Medicine 2018:686-3973.
5. Amoateng P, Kukuia KKE, Mensah JA, Osei-Safo D, Adjei S, Eklemet AA, Vinyo EA, Karikari TK: An extract of Synedrella nodiflora (L) Gaertn exhibits antidepressant properties through monoaminergic mechanisms. Metabolic Brain Disease 2018.
6. Amoateng P, Osei-Safo D, Kukuia KKE, Adjei S, Akure OA, Agbemelo-Tsomafo C, Adu-Poku SN, Agyeman-Badu KY: Psychotropic Effects of an Alcoholic Extract from the Leaves of Albizia zygia (Leguminosae-Mimosoideae). Evidence-Based Complementary and Alternative Medicine 2017, 2017:12.
7. Amoateng P, Adjei S, Osei-Safo D, Kukuia KKE, Kretchy IA, Sarkodie JA, N’Guessan BB: Analgesic effects of a hydro-ethanolic whole plant extract of Synedrella nodiflora (L.) Gaertn in paclitaxel-induced neuropathic pain in rats. BMC Research Notes 2017, 10(1):226.
8. Amoateng P, Adjei S, Osei-Safo D, Kukuia KKE, Karikari TK, Nyarko AK: An ethanolic extract of Desmodium adscendens exhibits antipsychotic-like activity in mice. Journal of Basic and Clinical Physiology and Pharmacology 2017.
9. Amoateng P, Adjei S, Osei-Safo D, Kukuia KKE, Bekoe EO, Karikari TK, Kombian SB: Extract of Synedrella nodiflora (L) Gaertn exhibits antipsychotic properties in murine models of psychosis. BMC Complementary and Alternative Medicine 2017, 17(1):389.
10. Gruca M, Yu W, Amoateng P, Nielsen MA, Poulsen TB, Balslev H: Ethnomedicinal survey and in vitro anti-plasmodial activity of the palm Borassus aethiopum Mart. Journal of Ethnopharmacology 2015, 175:356-369.
11. Amoateng P, Adjei S, Osei-Safo D, Ameyaw EO, Ahedor B, N'Guessan B B, Nyarko AK: A hydro-ethanolic extract of Synedrella nodiflora (L.) Gaertn ameliorates hyperalgesia and allodynia in vincristine-induced neuropathic pain in rats. Journal of Basic and Clinical Physiology and Pharmacology 2015, 26(4):383-394.
12. Ameyaw E, Boampong J, Kukuia K, Amoateng P, Obese E, Osei-Sarpong C, Woode E: Effect of xylopic acid on paclitaxel-induced neuropathic pain in rats. Journal of Medical and Biomedical Sciences 2014, 2(4):6-12
13. Amoateng P, Woode E, Kombian SB: Anticonvulsant and related neuropharmacological effects of the whole plant extract of Synedrella nodiflora (L.) Gaertn (Asteraceae). Journal of Pharmacy & Bioallied Sciences 2012, 4(2):140-148.
14. Woode E, Amoateng P, Abotsi WMK: Ethopharmacological analysis of the effects of the whole plant extract of Synedrella nodiflora (L.) Gaertn (Asteraceae) in murine models. Der Pharmacia Sinica 2011, 2 (2):54-67.
15. Woode E, Amoateng P, Ansah C, Duwiejua M: Anti-nociceptive effects of an ethanolic extract of the whole plant of Synedrella nodiflora (L.) Gaertn in mice: Involvement of adenosinergic mechanisms. Journal of Pharmacology and Toxicology 2009, 4:17-29.
2. Bekoe EO, Agyare C, Boakye YD, Baiden BM, Asase A, Sarkodie J, Nettey H, Adu F, Otu PB, Agyarkwa B, Amoateng P. Ethnomedicinal survey and mutagenic studies of plants used in Accra metropolis, Ghana. Journal of Ethnopharmacology 2019, 112309.
3. Amoateng P, Quansah E, Karikari TK, Asase A, Osei-Safo D, Kukuia KKE, Amponsah IK, Nyarko AK: Medicinal plants used in the treatment of mental and neurological disorders in Ghana. Evidence-Based Complementary & Alternative Medicine 2018.
4. Kukuia KKE, Mensah JA, Amoateng P, Amponsah SK, N'Guessan BB, Asiedu-Gyekye IJ: Antidepressant Potentials of Components from Trichilia monadelpha (Thonn.) J.J. de Wilde in Murine Models. Evidence-Based Complementary & Alternative Medicine 2018:686-3973.
5. Amoateng P, Kukuia KKE, Mensah JA, Osei-Safo D, Adjei S, Eklemet AA, Vinyo EA, Karikari TK: An extract of Synedrella nodiflora (L) Gaertn exhibits antidepressant properties through monoaminergic mechanisms. Metabolic Brain Disease 2018.
6. Amoateng P, Osei-Safo D, Kukuia KKE, Adjei S, Akure OA, Agbemelo-Tsomafo C, Adu-Poku SN, Agyeman-Badu KY: Psychotropic Effects of an Alcoholic Extract from the Leaves of Albizia zygia (Leguminosae-Mimosoideae). Evidence-Based Complementary and Alternative Medicine 2017, 2017:12.
7. Amoateng P, Adjei S, Osei-Safo D, Kukuia KKE, Kretchy IA, Sarkodie JA, N’Guessan BB: Analgesic effects of a hydro-ethanolic whole plant extract of Synedrella nodiflora (L.) Gaertn in paclitaxel-induced neuropathic pain in rats. BMC Research Notes 2017, 10(1):226.
8. Amoateng P, Adjei S, Osei-Safo D, Kukuia KKE, Karikari TK, Nyarko AK: An ethanolic extract of Desmodium adscendens exhibits antipsychotic-like activity in mice. Journal of Basic and Clinical Physiology and Pharmacology 2017.
9. Amoateng P, Adjei S, Osei-Safo D, Kukuia KKE, Bekoe EO, Karikari TK, Kombian SB: Extract of Synedrella nodiflora (L) Gaertn exhibits antipsychotic properties in murine models of psychosis. BMC Complementary and Alternative Medicine 2017, 17(1):389.
10. Gruca M, Yu W, Amoateng P, Nielsen MA, Poulsen TB, Balslev H: Ethnomedicinal survey and in vitro anti-plasmodial activity of the palm Borassus aethiopum Mart. Journal of Ethnopharmacology 2015, 175:356-369.
11. Amoateng P, Adjei S, Osei-Safo D, Ameyaw EO, Ahedor B, N'Guessan B B, Nyarko AK: A hydro-ethanolic extract of Synedrella nodiflora (L.) Gaertn ameliorates hyperalgesia and allodynia in vincristine-induced neuropathic pain in rats. Journal of Basic and Clinical Physiology and Pharmacology 2015, 26(4):383-394.
12. Ameyaw E, Boampong J, Kukuia K, Amoateng P, Obese E, Osei-Sarpong C, Woode E: Effect of xylopic acid on paclitaxel-induced neuropathic pain in rats. Journal of Medical and Biomedical Sciences 2014, 2(4):6-12
13. Amoateng P, Woode E, Kombian SB: Anticonvulsant and related neuropharmacological effects of the whole plant extract of Synedrella nodiflora (L.) Gaertn (Asteraceae). Journal of Pharmacy & Bioallied Sciences 2012, 4(2):140-148.
14. Woode E, Amoateng P, Abotsi WMK: Ethopharmacological analysis of the effects of the whole plant extract of Synedrella nodiflora (L.) Gaertn (Asteraceae) in murine models. Der Pharmacia Sinica 2011, 2 (2):54-67.
15. Woode E, Amoateng P, Ansah C, Duwiejua M: Anti-nociceptive effects of an ethanolic extract of the whole plant of Synedrella nodiflora (L.) Gaertn in mice: Involvement of adenosinergic mechanisms. Journal of Pharmacology and Toxicology 2009, 4:17-29.