IRB Faculty

The Medical &
Scientific Research Directorate

...
Dr. Nicholas Ekow Thomford

BSc, MPhil, PhD

Senior Lecturer

nthomford@ucc.edu.gh | 0244797595 |

Education

  • Master of Philosophy in Medical Biochemistry at the University of Ghana  
  • Human Genetics, University of Cape Town (2014 - 2017) 
  • Biochemistry at the University of Ghana

Research Interest

 My research interests focus on:  

Current projects
  1. Immunogenetics of HBV Principal Investigator January 2021 - Present
  2. Pharmacomicrobiomics of Malaria-HIV co-infections Principal Investigator January 2020 - Present 
  3. Cardiogenetic Principal Investigator January 2019 - Present 
  4. Pre-eclampsia genetics    Co-PI January 2018 - Present

Selected Publications

  1. Beaverson, K. L., Julkowska, D., Letinturier, M. C. V., Aartsma-Rus, A., Austin, J., Bueren, J., ... & Hartman, A. L. (2023). The IRDiRC Chrysalis Task Force: making rare disease research attractive to companies. Therapeutic Advances in Rare Disease, 4, 26330040231188979. 
  2. Dzobo, K., Thomford, N. E., Senthebane, D. A., Shipanga, H., Rowe, A., Dandara, C., ... & Motaung, K. S. C. M. (2018). Advances in regenerative medicine and tissue engineering: innovation and transformation of medicine. Stem cells international, 2018. 
  3. Agamah, F. E., Mazandu, G. K., Hassan, R., Bope, C. D., Thomford, N. E., Ghansah, A., & Chimusa, E. R. (2020). Computational/in silico methods in drug target and lead prediction. Briefings in bioinformatics, 21(5), 1663-1675. 
  4. Senthebane, D. A., Jonker, T., Rowe, A., Thomford, N. E., Munro, D., Dandara, C., ... & Dzobo, K. (2018). The role of tumor microenvironment in chemoresistance: 3D extracellular matrices as accomplices. International journal of molecular sciences, 19(10), 2861. 
  5. Dzobo, K., Senthebane, D. A., Ganz, C., Thomford, N. E., Wonkam, A., & Dandara, C. (2020). Advances in therapeutic targeting of cancer stem cells within the tumor microenvironment: an updated review. Cells, 9(8), 1896.  
  6. Awany, D., Allali, I., Dalvie, S., Hemmings, S., Mwaikono, K. S., Thomford, N. E., ... & Chimusa, E. R. (2019). Host and microbiome genome-wide association studies: current state and challenges. Frontiers in genetics, 9, 637.  
  7. Dzobo, K., Adotey, S., Thomford, N. E., & Dzobo, W. (2020). Integrating artificial and human intelligence: a partnership for responsible innovation in biomedical engineering and medicine. Omics: a journal of integrative biology, 24(5), 247-263.         
  8. Thomford, N. E., Bope, C. D., Agamah, F. E., Dzobo, K., Owusu Ateko, R., Chimusa, E., ... & Wonkam, A. (2020). Implementing artificial intelligence and digital health in resource-limited settings? Top 10 lessons we learned in congenital heart defects and cardiology. Omics: a journal of integrative biology, 24(5), 264-277.  
  9. Dzobo, K., Thomford, N. E., & Senthebane, D. A. (2019). Targeting the versatile Wnt/β-catenin pathway in cancer biology and therapeutics: from concept to actionable strategy. Omics: a journal of integrative biology, 23(11), 517-538.  
  10. Kuguyo, O., Tsikai, N., Thomford, N. E., Magwali, T., Madziyire, M. G., Nhachi, C. F., ... & Dandara, C. (2018). Genetic susceptibility for cervical cancer in African populations: what are the host genetic drivers? OMICS: A journal of integrative Biology, 22(7), 468-483. 
  11. Thomford, N. E., Dzobo, K., Adu, F., Chirikure, S., Wonkam, A., & Dandara, C. (2018). Bush mint (Hyptis suaveolens) and spreading hogweed (Boerhavia diffusa) medicinal plant extracts differentially affect activities of CYP1A2, CYP2D6 and CYP3A4 enzymes. Journal of ethnopharmacology, 211, 58-69.  
  12. Dzobo, K., Senthebane, D. A., Rowe, A., Thomford, N. E., Mwapagha, L. M., Al-Awwad, N., … & Parker, M. I. (2016). Cancer stem cell hypothesis for therapeutic innovation in clinical oncology? Taking the root out, not chopping the leaf. Omics: a journal of integrative biology, 20(12), 681-691.   
  13. Thomford, N. E., Senthebane, D. A., Rowe, A., Munro, D., Seele, P., Maroyi, A., & Dzobo, K. (2018). Natural products for drug discovery in the 21st century: innovations for novel drug discovery. International journal of molecular sciences, 19(6), 1578.  
  14. Senthebane, D. A., Rowe, A., Thomford, N. E., Shipanga, H., Munro, D., Al Mazeedi, M. A., ... & Dzobo, K. (2017). The role of tumor microenvironment in chemoresistance: to survive, keep your enemies closer. International journal of molecular sciences, 18(7), 1586 ·   
  15. Thomford, N. E., Dzobo, K., Chopera, D., Wonkam, A., Skelton, M., Blackhurst, D., ... & Dandara, C. (2015). Pharmacogenomics implications of using herbal medicinal plants on African populations in health transition. Pharmaceuticals, 8(3), 637-663.  

Get in touch

Email Addresses:
info-msrc@ugmc.ug.edu.gh